Wei Lu

PhD student, Rice University

1 paper at NeurIPS 2025

OpenReview· Semantic Scholar· Google Scholar

Poster Session 4

1 paper

Thursday, December 4, 2025 · 4:30 PM → 7:30 PM

Exhibit Hall C,D,E

Accurately Predicting Protein Mutational Effects via a Hierarchical Many-Body Attention Network

#1715 · Dahao Xu, Jiahua Rao, Mingming Zhu, Jixian Zhang, Wei Lu, Shuangjia Zheng, Yuedong Yang

We present H3-DDG, a model that predicts binding free energy changes by modeling higher-order many-body interactions, achieving state-of-the-art performance in protein mutational effect prediction.